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FIRST CLINICAL TRIAL SPONSORED BY BIOZEUS CONCLUDED!

FIRST CLINICAL TRIAL SPONSORED BY BIOZEUS CONCLUDED!

The Clinical Trial was performed at Scentryphar, in Campinas/São Paulo.

The “Clinical study in healthy subjects to investigate the safety of BZ371 in the treatment of erectile dysfunction” has the objective to evaluate topical BZ371 for (i) safety, (ii) bioavailability and (iii) preliminary efficacy in healthy male and female subjects.

Topical administration of BZ371 was well tolerated in all subjects tested. There was no local irritation, edema, headache, hypotension, ECG changes, blood hemogram, prolonged erection, priapism or penile pain. Doppler scan demonstrated an increase in penile arterial inflow in subjects who received 2 mg/ml of treatment, compared to placebo (approximately a 113% increase, as demonstrated in figure 1) at 30 min following the application, compatible with preclinical studies of the mechanism of action and permeation.

BZ371 has the potential to be a safe and efficacious option for erectile dysfunction patients.